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| Registros recuperados : 43 | |
| 41. |  | SILVA, M. R.; PELISSARI, A.; MORAES, A. de; SANDINI, I. E.; CASSOL, L. C.; ASSMANN, T. S.; OLIVEIRA, E. B. de. Acumulação de nutrientes e produção forrageira de aveia e azevém em função da aplicação de calcário e gesso em superfície. Revista de Ciências Agrárias, Lisboa, v.38, n.3, p. 346-356, set. 2015.| Biblioteca(s): Embrapa Florestas. |
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| Registros recuperados : 43 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Amazônia Ocidental; Embrapa Pesca e Aquicultura; Embrapa Recursos Genéticos e Biotecnologia. |
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Data corrente: |
29/08/2022 |
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Data da última atualização: |
29/08/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 2 |
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Autoria: |
PAIXÃO, R. V.; SILVA, G. F. da; CAETANO, A. R.; CINTRA, L. C.; VARELA, E. S.; O'SULLIVAN, F. L. A. |
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Afiliação: |
R. V. PAIXÃO, UNIVERSIDADE FEDERAL DO AMAZONAS; GILVAN FERREIRA DA SILVA, CPAA; ALEXANDRE RODRIGUES CAETANO, Cenargen; LEANDRO CARRIJO CINTRA, CNPTIA; EDUARDO SOUSA VARELA, CNPASA; FERNANDA LOUREIRO ALMEIDA OSULLIVAN, CPAA. |
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Título: |
Phylogenomic and expression analysis of Colossoma macropomum cyp19a1a and cyp19a1b and their non-classical role in tambaqui sex differentiation. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Gene, v. 843, art. 146795, Nov. 2022. |
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DOI: |
https://doi.org/10.1016/j.gene.2022.146795 |
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Idioma: |
Inglês |
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Conteúdo: |
The genes coding for Cytochrome P450 aromatase (cyp19a1a and cyp19a1b) and estrogen (E2) receptors (esr1, esr2a and esr2b) play a conserved role in ovarian differentiation and development among teleosts. Classically, the "gonad form" of aromatase, coded by the cyp19a1a, is responsible for the ovarian differentiation in genetic females via ligation and activation of the Esr, which mediates the endocrine and exocrine signaling to allow or block the establishment of the feminine phenotype. However, in neotropical species, studies on the molecular and endocrine processes involved in gonad differentiation as well as on the effects of sex modulators are recent and scarce. In this study, we combined in silico analysis, real-time quantitative PCR (qPCR) assay and quantification of E2 plasma levels of differentiating tambaqui (Colossoma macropomum) to unveil the roles of the paralogs cypa19a1a and cyp19a1b during sex differentiation. |
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Palavras-Chave: |
Cyp19a1; Neotropical fish; Promoter Structure; Sex development; Synteny. |
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Thesagro: |
Colossoma Macropomum; Tambaqui. |
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Thesaurus NAL: |
Aromatase; Colossoma; Fish; Phylogeny. |
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Categoria do assunto: |
--
L Ciência Animal e Produtos de Origem Animal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1145818/1/1-s2.0-S037811192200614X-main.pdf
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Marc: |
LEADER 01900naa a2200325 a 4500
001 2145818
005 2022-08-29
008 2022 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/j.gene.2022.146795$2DOI
100 1 $aPAIXÃO, R. V.
245 $aPhylogenomic and expression analysis of Colossoma macropomum cyp19a1a and cyp19a1b and their non-classical role in tambaqui sex differentiation.$h[electronic resource]
260 $c2022
520 $aThe genes coding for Cytochrome P450 aromatase (cyp19a1a and cyp19a1b) and estrogen (E2) receptors (esr1, esr2a and esr2b) play a conserved role in ovarian differentiation and development among teleosts. Classically, the "gonad form" of aromatase, coded by the cyp19a1a, is responsible for the ovarian differentiation in genetic females via ligation and activation of the Esr, which mediates the endocrine and exocrine signaling to allow or block the establishment of the feminine phenotype. However, in neotropical species, studies on the molecular and endocrine processes involved in gonad differentiation as well as on the effects of sex modulators are recent and scarce. In this study, we combined in silico analysis, real-time quantitative PCR (qPCR) assay and quantification of E2 plasma levels of differentiating tambaqui (Colossoma macropomum) to unveil the roles of the paralogs cypa19a1a and cyp19a1b during sex differentiation.
650 $aAromatase
650 $aColossoma
650 $aFish
650 $aPhylogeny
650 $aColossoma Macropomum
650 $aTambaqui
653 $aCyp19a1
653 $aNeotropical fish
653 $aPromoter Structure
653 $aSex development
653 $aSynteny
700 1 $aSILVA, G. F. da
700 1 $aCAETANO, A. R.
700 1 $aCINTRA, L. C.
700 1 $aVARELA, E. S.
700 1 $aO'SULLIVAN, F. L. A.
773 $tGene$gv. 843, art. 146795, Nov. 2022.
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Registro original: |
Embrapa Amazônia Ocidental (CPAA) |
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